OK, now I can finally answer this having seeing them both... Brenda is more of the easy going, easy to relate to girl, she's a fun character, a bit overdramatic... Prue is in a completely different league. Stronger, has more serious problems and more of a role model.. And since Charmed is one of my fave shows and I loved Prue and Piper the most, it'll have to be Prue... Although Brenda is really cool too